SHAWN M. BAUER,ZHAOZHONG J. JIA,MUKUND MEHROTRA,YONGHONG SONG,QING XU,WOLIN HUANG,CHANDRASEKAR VENKATARAMANI,JACK W. ROSE,ANJALI PANDEY
申请号：
US16696175
公开号：
US20200239458A1
申请日:
2019.11.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention is directed to compounds of formula I-II and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
