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HÉTÉROCYCLE CONTENANT DE L'AZOTE AYANT UNE ACTIVITÉ INHIBITRICE DE TRKA ET DÉRIVÉ CARBOCYCLIQUE
专利权人:
Shionogi & Co.; Ltd.
发明人:
YUKIMASA, Akira,KANO, Kazuya,HORIGUCHI, Tohru,NAKAMURA, Kenichiroh,INOUE, Takatsugu,FUJIU, Motohiro,YAMAGUCHI, Hiroki
申请号:
EP17747550
公开号:
EP3412663A4
申请日:
2017.02.03
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention provides a compound having TrkA inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein =X is =O or the like, R 5 and R 5A are hydrogen atoms or the like, -A- is -NR 1 - or the like, B is substituted or unsubstituted aromatic carbocyclyl or the like, R 1 is substituted or unsubstituted alkyl or the like, R 2 is a hydrogen atom or the like, -W-is -CH 2 - or the like, -W A - is -CH 2 - or the like, R 13 is substituted or unsubstituted aromatic carbocyclyl or the like, R 14 is substituted or unsubstituted aromatic heterocyclyl or the like, R 15 is substituted or unsubstituted alkyl or the like, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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