PROBLEM TO BE SOLVED: To provide a medicament for preventing or treating diseases and accompanying symptoms thereof in a patient suffering from ophthalmic diseases caused by a retinal disorder other than optic nerve cell damages to allow prevention of the progression of vision disorders, as well as to allow prevention or treatment of such diseases.SOLUTION: A medicament for preventing or treating ophthalmic diseases and accompanying symptoms thereof, which are caused by a retinal disorder other than optic nerve cell damages. The medicament comprises, as effective ingredients, a sigma receptor ligand or a salt thereof, preferably cutamesine (1- [2- (3,4-dimethoxyphenyl) ethyl]-4- (3-phenylpropyl) piperazine).SELECTED DRAWING: None【課題】視神経細胞障害以外の、網膜の障害に起因する眼科疾患を患う患者において、該疾患及びそれに随伴する症状を予防又は治療し、もって視力障害の進展の防止、予防あるいは治療を可能とするための医薬を提供する。【解決手段】シグマ受容体リガンド又はそれらの塩、好ましくは、クタメシン(1-[2-(3,4-ジメトキシフェニル)エチル]-4-(3-フェニルプロピル)ピペラジン)を有効成分とする、視神経細胞障害以外の、網膜の障害に起因する眼科疾患および該疾患に随伴する症状の、予防又は治療のための医薬。【選択図】なし