Michael Salerno,Craig H. Meyer,Xiao Chen,Yang Yang,Frederick H. Epstein,Christopher M. Kramer
申请号:
US14952859
公开号:
US09953439B2
申请日:
2015.11.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Some aspects of the present disclosure relate to systems and methods for three-dimensional spiral perfusion imaging. In one embodiment, a method for perfusion imaging of a subject includes acquiring perfusion imaging data associated with the heart of a subject. The acquiring includes applying an imaging pulse sequence with a three-dimensional stack-of-spirals trajectory. The method also includes reconstructing perfusion images from the acquired perfusion imaging data. The reconstructing includes parallel imaging and motion-guided compressed sensing. The method also includes determining, from the reconstructed perfusion images, absolute perfusion values based on time-intensity relationships to quantify myocardial blood flow of the heart of the subject, and generating a quantitative volumetric perfusion flow map based on the determined absolute perfusion values.