Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions

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专利权人:

发明人:

申请号：

EP10181619.7

公开号：

EP2275094A3

申请日:

1996.09.25

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Disclosed are methods of intravenous administration of nanoparticulate drug formulations to a mammal to avoid adverse hemodynamic effects: by reducing the rate and concentration of the nanoparticles in the formulations or by pretreating the subject with histamine or by pretreating the subject with a desensitizing amount of the nanoparticulate drug formulations.

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