This Hair bright Ti Gong mono- Seed radiation Line controls Treatment and increases Strong Elixirs, Ke With cancers radiate Treatment methods And Yong Er Minus radiates Line amounts, Yi Ke Minus Light side effects less. Above-mentioned radiation Line controls Treatment increasings Strong Elixirs Department and makees As effective components with Suo Rong Xu Which on uracil derivative or its Drug Learn, and The uracil Yan Sheng Wu Department are indicated with general formula (1)[in formula, R1Biao Shi Halogen elements atoms or cyanoR2Indicate 4 ~ 8 STAFF Miscellaneous Ring bases containing 1 ~ 3 Ge nitrogen-atoms that can have low-carbon Number alkyl, Asia amido, Hydroxyalkyl Ji, Hydroxyalkyl ylmethyls, methylsulphur acyloxy grp or amido to make As substituent groups, Hydrogen atoms on nitrogen-atoms can be by the alkyl-substituted amidine sulfenyls of low-carbon Number, the guanidine radicals that Hydrogen atoms on nitrogen-atoms can be replaced by low-carbon Number alkyl or cyano, low-carbon Number alkyl amidines or 1- Pyrrolizidines ylmethyl].本發明提供一種放射線治療增強劑,其可與癌放射療法併用而減少放射線量,亦可減輕副作用。上述放射線治療增強劑係以尿嘧啶衍生物或其在藥學上所容許之鹽作為有效成分,該尿嘧啶衍生物係以通式(1)表示[式中,R1表示鹵素原子或氰基;R2表示可具有低碳數烷基、亞胺基、羥基、羥基甲基、甲磺醯氧基或胺基作為取代基之含有1~3個氮原子的4~8員雜環基,氮原子上之氫原子可被低碳數烷基取代的脒硫基,氮原子上之氫原子可被低碳數烷基或氰基取代的胍基,低碳數烷基脒基,或1-吡咯啶基甲基]。
