This Hair bright Mu Department Ti Gong mono- antimycotic Elixirs of Seed, with Gifted good antimycotic effect Should and its physical characteristic, safety Ji the qualitative Yi Very As Gifted of Dai Xie Steady are good.This Hair of root According is bright, discloses a Seed by the change of lower formula (I) expression and closes object or its Which:Wherein R1Indicate Hydrogen Yuan, Halogen elements atom, amido, C1-6Alkyl, C1-6Alkoxy or C1-6Alkoxy C 1-6AlkylR2Indicate Hydrogen atoms, C1-6Alkyl, amido or two C1-6Alkyl amine groupThe one As nitrogen-atoms of X and Y, and another one As nitrogen-atoms or oxygen atomRing A expressions Ke have You Halogen elements atoms or a 1 or 2 Ge C1-65 STAFF of alkyl or 6 STAFF Miscellaneous Fang Ji Ring Huo Ben RingZ indicates Yi Single Key, Asia methyl, stretches ethyl, oxygen atom, sulphur atom ,-CH2O- ,-OCH2,-NH- ,-CH2NH- ,-NHCH2,-CH2S- or-SCH2?R3The C1-6 for indicating Hydrogen Yuan, Halogen elements atom, can having 1 or 2 Ge substituent groupsAlkyl, C3-8Ring alkyl, C6-10Aryl, 5 STAFF or 6 STAFF Miscellaneous aryl or 5 STAFF or 6 STAFF non-Fang Zu Miscellaneous Ring basesAnd R4Indicate Hydrogen Yuan Huo Halogen element atoms.本發明之目的係提供一種抗真菌劑,其具有優良的抗真菌效應且其物理特性、安全性及代謝穩定性亦極為優良。根據本發明,揭示一種由下式(I)表示之化合物或其鹽:其中R1表示氫原子、鹵素原子、胺基、C1-6烷基、C1-6烷氧基或C1-6烷氧基C1-6烷基;R2表示氫原子、C1-6烷基、胺基或二C1-6烷基胺基;X及Y之一者為氮原子,而另一者為氮原子或氧原子;環A表示可具有鹵素原子或1或2個C1-6烷基之5員或6員雜芳基環或苯環;Z表示一單鍵、亞甲基、伸乙基、氧原子、硫原子、-CH2O-、-OCH2-、-NH-、-CH2NH-、-NHCH2-、-CH2S-或-SCH2-;R3表示氫原子、鹵素原子、可具有1或2個取代基之C1-6烷基、C3-8環烷基、C6-10芳基、5員或6員雜芳基或5員或6員非芳族雜環基;且R4表示氫原子或鹵素原子。
