Formulations for inhibition of PCSK9 for the treatment of hypercholesterolemia

• 收藏
• 分享

专利权人:

Heart Biotech Limited

发明人:

Magdi Habib Yacoub,Ibrahim M El Sherbiny

申请号：

GB201506654

公开号：

GB2537614A

申请日:

2015.04.20

申请国别(地区):

GB

年份:

2016

代理人:

摘要：

Described herein are pharmaceutical formulations for the treatment of hypercholesterolemia, comprising nanoparticles having a polymeric hydrophobic core which is associated with an inhibitor of PCSK9. The inhibitor may be EGF-A, EGF-B, or an siRNA. Preferred polymers include chitosan. The nanoparticle may further include a hydrophilic shell coating the core. The core may be porous.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/