COX Christopher D.,DUDKIN Vadim,KERN Jeffrey,LAYTON Mark E.,RAHEEM Izzat T.
申请号:
SI201230539
公开号:
SI2748151T1
申请日:
2012.08.20
申请国别(地区):
SI
年份:
2016
代理人:
摘要:
The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.