The invention relates to an herbicidal composition for weed control, particularly in corn, wherein the herbicidal composition comprises mesotrione and at least one second herbicidal agent selected from the group consisting of nicosulfuron, dicamba, imazaquin, their salts and any combination thereof. The invention also relates to the methods using the compositions for controlling undesirable vegetation.本發明涉及一種用以控制雜草(尤其在玉米的雜草)的除草組合物。該除草組合物含有硝草酮以及最少一種第二除草劑選自煙嘧磺隆、汰克草、滅草喹、其鹽及其任何組合。本發明亦涉及一種使用本組合物控制有害植物的方法。