THE PROVOST; FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH; NEAR DUBLIN
发明人:
GILMER, JOHN FRANCIS,CLUNE-MORIARTY, LOUISE,LALLY, MAEVE
申请号：
NZ58630408
公开号：
NZ586304A
申请日:
2008.12.19
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Disclosed herein is an isosorbide aspirinate compound of the given general formula, wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds relate to potent aspirin prodrugs which are stable to moisture and towards conditions encountered in the lumen of the GI tract which breaks down rapidly during and after absorption to release aspirin and/or nitric oxide (NO).
