Thomas E. Albrecht,Jeffrey L. Aldridge,Sean P. Conlon,Michael S. Cropper,Denzel Z. Herrera-Davis,Daniel F. Dlugos, Jr.,Jason L. Harris,Christopher J. Hess,Prasanna Malaviya,Glenda C. Marsh,Mark S. Ort
申请号:
US13104313
公开号:
US08876761B2
申请日:
2011.05.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.