A medical nanoparticle(s) includes a first core, a first outer lipid layer, a first inner lipid layer, and a nucleic acid. The first core includes a bio-degradable ionic precipitate (BIP). The first inner lipid layer is between the first core and the first outer lipid layer. The nucleic acid is at the surface of the core, and the nucleic acid includes the sequence set forth in SEQ ID NO: 1..一種醫用奈米粒子組，包含一第一核心、一第一外脂層、一第一內脂層以及一核酸。第一核心包含生物可降解離子沉澱物（Bio-degradable ionic precipitate, BIP）。第一內脂層位於第一核心與第一外脂層之間。核酸位於核心表面，核酸包括序列編號：1的核苷酸序列。
