GlaxoSmithKline Intellectual Property Development Limited
发明人:
Emilio ALVAREZ-RUIZ,Andrew John COLLIS,Alison Sarah DANN,Andrew Peter FOSBERRY,Sarah Jane READY,Maria Jesus VAZQUEZ MUNIZ
申请号：
US15118924
公开号：
US20160355856A1
申请日:
2015.02.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the microorganisms used in this process. The invention also comprises migalastat produced according to the above method and pharmaceutical compositions and uses thereof.
