GlaxoSmithKline Intellectual Property Development Limited
发明人:
Alvarez-Ruiz, Emilio,Collis, Andrew John,Dann, Alison Sarah,Fosberry, Andrew Peter,Ready, Sarah Jane,Vazquez Muniz, Maria Jesus
申请号:
AU2015216909
公开号:
AU2015216909B2
申请日:
2015.02.17
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the microorganisms used in this process. The invention also comprises migalastat produced according to the above method and pharmaceutical compositions and uses thereof.