An aqueous nicotine solution for use in an active mesh nebulizer as part of a smoking cessation program, or as a substitute for tobacco use, includes nicotine in water with a nicotine concentration ranging from about 1.0 milligram (mg) nicotine per milliliter (ml) of water (e.g., 0.01% nicotine), to about 0.005 mg nicotine per milliliter of water (about 0.0005% nicotine). The pH of the aqueous nicotine solution ranges from about 3.5 to about 12 because the plume of particles of aqueous nicotine solution produced by the active mesh nebulizer are entrained with the inhaled air and do not impact the walls of the throat or lungs. The aqueous nicotine solution is free from metals because it is delivered to a user at room temperature, without heating or boiling.
