The Regents of the University of Colorado; a body corporate
发明人:
Michael V. Holers,Nirmal Banda,Liudmila Kulik
申请号：
US15316113
公开号：
US20170209549A1
申请日:
2015.06.04
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides delivery methods and constructs for treating inflammatory diseases in an individual. The targeted delivery approach utilizes an antibody that recognizes an epitope found to be present at sites of inflammation. The antibody is used to deliver a MAp44 polypeptide or fragment thereof to sites of inflammation, where it inhibits the lectin pathway of complement activation.
