Die Erfindung betrifft einen antiinfektiven Abstandhalter (1) für Osteosyntheseplatten umfassend eine Platte mit mindestens einer Ausnehmung (2) zur Aufnahme einer Schraube, wobei die Platte aus mindestens einem biokompatiblen Material aufgebaut ist, in dem mindestens eine antimikrobielle Substanz verteilt, dispergiert oder gelöst ist. Die Erfindung betrifft auch ein Set umfassend zumindest eine Ostheosyntheseplatte und zumindest einen solchen Abstandhalter, vorzugsweise umfassend wenigstens eine Schraube für jede Ausnehmung jedes Abstandhalters.The antiinfective spacer (1) comprises a plate having a recess (2) for receiving a screw, where the plate is composed of a biocompatible material in which an antimicrobial substance is distributed, dispersed or dissolved. An amount and/or concentration of the antimicrobial substance is contained into the biocompatible material, and an anti-microbial effect of the material is achieved in a region around a surface of the plate. The spacer has a side of point- or strip-shaped projections. The spacer is composed of a plastic, a porous metal and/or a porous ceramic. The antiinfective spacer (1) comprises a plate having a recess (2) for receiving a screw, where the plate is composed of a biocompatible material in which an antimicrobial substance is distributed, dispersed or dissolved. An amount and/or concentration of the antimicrobial substance is contained into the biocompatible material, and an anti-microbial effect of the material is achieved in a region around a surface of the plate. The spacer has a side of point- or strip-shaped projections. The spacer is composed of a plastic, a porous metal and/or a porous ceramic. X-ray opacifiers are dispersed in the plastic. The plastic contains an active substance release-promoting additive. The pores are interconnected in the metal, and the porous metal have a diameter of 1-100 mu m. The ceramic material has a diameter of 1-100 mu m. The amount of the antimicrobial substance is 0.1-2