ALLEGRETTI, PAUL,CHOI, SEOK-KI,GENDRON, ROLAND,FATHEREE, PAUL R.,JENDZA, KEITH,MCKINNELL, ROBERT MURRAY,MCMURTRIE, DARREN,OLSON, BROOKE
申请号:
DK08743204
公开号:
DK2146963T3
申请日:
2008.04.23
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
The invention is directed to compounds having the formula: wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.