PAUL ALLEGRETTI,SEOK-KI CHOI,ROLAND GRENDRON,PAUL ROSS FATHEREE,KEITH JENDZA,ROBERT MURRAY MCKINNELL,DARREN MCMURTRIE,BROOKE OLSON
申请号：
BRPI0810813
公开号：
BRPI0810813A2
申请日:
2008.04.23
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The invention is directed to compounds having the formula: wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds； methods of using such compounds； and process and intermediates for preparing such compounds.
