A vascular measurement system is provided to perform various types of peripheral vascular measurements to evaluate at least one of arterial blood flow and venous blood flow. The system includes a plurality of ports configured to connect a plurality of inflatable cuffs, an inflation device, a deflation device, and a volume measuring device configured to withdraw a predetermined volume of air contained in at least one of the first and second inflatable cuffs and resupply the predetermined volume of air into the at least one of the first and second inflatable cuffs.