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Agent for treatment or prevention of diseases associated with activity of neurotrophic factors
专利权人:
Junichi Ishikawa;Kentaro Kobayashi;Koichi Saito;Norihisa Ohe
发明人:
Junichi Ishikawa,Koichi Saito,Norihisa Ohe,Kentaro Kobayashi
申请号:
US13322888
公开号:
US08829035B2
申请日:
2010.05.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A compound depicted by the formula below, or a pharmaceutically acceptable salt or solvate thereof.wherein, R1 represents (1) a C3-6 alkyl group, (2) a C1-6 alkyl group substituted with one or more substituent group(s) selected from those consisting a halogen atom, etc., (3) a C3-10 non-aromatic cyclic hydrocarbon group or a 5- to 6-membered non-aromatic heterocyclic group which respectively is optionally substituted with one or more substituent group(s) selected from those consisting an oxo group, etc., (4) an aromatic cyclic hydrocarbon group substituted with one or more substituent selected from the group consisting halogen atom and C1-4 alkoxy group; X represents NH, O, or S; Y represents CH or N; Z represents N or a C—R2; R2 represents (1) hydrogen atom, (2) a C1-6 alkyl group, a C2-6 alkenyl group or a C2-6 alkynyl group that respectively is optionally substituted with one or more substituent group(s) selected from among those consisting (a) a halogen atom, etc., or (3) a C5-6 non-aromatic cyclic hydrocarbon group or a 5- to 6-membered non-aromatic heterocyclic group optionally substituted; ring A represents a benzene ring optionally substituted; ring B represents a benzene ring optionally substituted.
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