The present invention is a method for producing a vesicle composition having an aqueous phase as a continuous phase, the method including a step of dissolving an oil phase containing component (A) a branched fatty acid having a predetermined structure; component (B) a tertiary amine having a predetermined structure; and component (C) an organic acid having 1 to 10 carbon atoms at a temperature that is equal to or higher than a melting point of the oil phase, and a step of carrying out mixing while adding the aqueous phase to the oil phase which is dissolved.