Woodside, Darren,Vanderslice, Peter,Market, Robert,Biediger, Ronald,Dixon, Richard,Willerson, James T.,Annapragada, Ananth,Tanifum, Eric
申请号：
AU2018258681
公开号：
AU2018258681A1
申请日:
2018.04.27
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Disclosed herein is a composition comprising a plurality of liposomes having an average diameter of less than 400 nanometers, wherein the plurality of liposomes comprise: a first lipid or phospholipid； a second lipid or phospholipid which is derivatized with a polymer； and a sterically bulky excipient capable of stabilizing the liposomes； a third lipid or phospholipid derivatized with a polymer terminated with an integrin targeting component； DSPE or a fourth lipid or phospholipid derivatized with a group binding a contrast enhancing agent wherein the plurality of liposomes optionally encapsulates a payload component consisting of one or more bioactive agents.
