WOODSIDE, DARREN,VANDERSLICE, PETER,MARKET, ROBERT,BIEDIGER, RONALD,DIXON, RICHARD,WILLERSON, JAMES T.,ANNAPRAGADA, ANANTH,TANIFUM, ERIC
申请号：
CA3061174
公开号：
CA3061174A1
申请日:
2018.04.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed herein is a composition comprising a plurality of liposomes having an average diameter of less than 400 nanometers, wherein the plurality of liposomes comprise: a first lipid or phospholipid； a second lipid or phospholipid which is derivatized with a polymer； and a sterically bulky excipient capable of stabilizing the liposomes； a third lipid or phospholipid derivatized with a polymer terminated with an integrin targeting component； DSPE or a fourth lipid or phospholipid derivatized with a group binding a contrast enhancing agent wherein the plurality of liposomes optionally encapsulates a payload component consisting of one or more bioactive agents.
