An interluminal medical treatment device (100) configured to treat a targeted treatment site within a body lumen (190). The interluminal medical treatment device can include an elongated generally tubular outer member (110). The outer member can include an expandable distal portion (110b), an expandable proximal portion (110a), and a central portion (110c) of limited expandability. The interluminal medical treatment device can include at least one membrane (120). The outer member and at least one membrane may define a housing area (130) positioned between the proximal portion and distal portion of the outer member. The outer member and at least one membrane can be configured to redirect fluid flow within a body lumen away from the housing area inner member or inner passageway.
