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Variants of group 5 allergens of the true grasses having reduced allergeneity due to mutagenesis of proline residues
专利权人:
Martin Wald
发明人:
Martin Wald,Andreas Nandy,Helmut Fiebig,Bernhard Weber,Helga Kahlert,Gerald Reese,Oliver Cromwell
申请号:
US13522093
公开号:
US09975932B2
申请日:
2010.12.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to the preparation and use of recombinant variants of group 5 allergens of the Poaceae (true grasses), which are characterized by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes.
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