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VARIANTS OF GROUP 6 ALLERGENS OF THE TRUE GRASSES HAVING REDUCED ALLERGENEITY DUE TO MUTAGENESIS OF PROLINE RESIDUES
专利权人:
发明人:
Martin WALD,Andreas NANDY,Helmut FIEBIG,Bernhard WEBER,Helga KAHLERT,Gerald REESE,Oliver CROMWELL
申请号:
US14546706
公开号:
US20150071953A1
申请日:
2014.11.18
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to the preparation and use of recombinant variants of group 6 allergens of the Poaceae (true grasses), which are characterised by reduced IgE reactivity compared with known wild-type allergens and at the same time substantially retained reactivity with T-lymphocytes.
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