Ron L. Hale,Craig C. Hodges,Peter M. Lloyd,Daniel Mufson,Daniel D. Rogers,Soonho Song,Martin J. Wensley,Daniel J. Myers,Jeffrey A. McKinney,Reynaldo J. Quintana,Joshua D. Rabinowitz
申请号:
US14077015
公开号:
US09439907B2
申请日:
2013.11.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present application relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition of a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method involves: (a) heating a substrate coated with a composition of a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.