Ron L. Hale,Craig C. Hodges,Peter M. Lloyd,Daniel Mufson,Daniel D. Rogers,Soonho Song,Martin J. Wensley,Daniel J. Myers,Jeffrey A. McKinney,Reynaldo J. Quintana,Joshua D. Rabinowitz
申请号：
US13851577
公开号：
US08955512B2
申请日:
2013.03.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick； and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method comprises: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg； and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy.
