Gronberg, Alvar,Dieterich, Christine,Mahlapuu, Margit
申请号：
AU2014351607
公开号：
AU2014351607A1
申请日:
2014.11.19
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present invention provides a pharmaceutical formulation comprising LL-37 or a pharmaceutically-acceptable salt thereof and one or more pharmaceutically-acceptable diluent or carrier system, for use in a method of treatment of a chronic ulcer wound (such as a hard- to-heal venous leg ulcer or a diabetic foot ulcer), which method comprises: (a) topical application of said formulation to said ulcer followed by (b) application of a dressing, and wherein said application of said formulation provides for a dose of LL-37 at the wound site that is below about 80 μg of LL-37 applied per cm2 of wound area, and/or below about 26.7 μg of LL-37 applied per cm
