Henricus Jacobus Maria Gijsen;Didier Jean-Claude Berthelot;Sven Franciscus Anna Van Brandt;Michel Anna Jozef De Cleyn;Daniel Oehlrich
发明人:
Michel Anna Jozef De Cleyn,Sven Franciscus Anna Van Brandt,Henricus Jacobus Maria Gijsen,Didier Jean-Claude Berthelot,Daniel Oehlrich
申请号:
US13522430
公开号:
US20120295901A1
申请日:
2011.01.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is concerned with novel substituted bicyclic triazole derivatives of Formula (I)wherein Het1, R1, R2, A1, A2, A3, A4, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.