Henricus Jacobus Maria Gijsen;Didier Jean-Claude Berthelot;Sven Franciscus Anna Van Brandt;Michel Anna Jozef De Cleyn;Michel Surkyn
发明人:
Sven Franciscus Anna Van Brandt,Michel Anna Jozef De Cleyn,Henricus Jacobus Maria Gijsen,Didier Jean-Claude Berthelot,Michel Surkyn
申请号:
US13522409
公开号:
US20120295891A1
申请日:
2011.01.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is concerned with novel substituted triazole derivatives of Formula (I)wherein Het1, R1, R2, A1, A2, A3, A4, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.