What is provided is a method of treating a patient having a tumor comprising administering an effective amount of adenosine deaminase, preferably polyalkylene oxide conjugated, to a patient in need thereof.本發明係提供一種治療具有腫瘤之患者的方法,其包含將有效量之腺苷脫胺酶(較佳地經聚伸烷基氧化物共軛)投藥予需要其之患者。