Antibody species that bind B-Cell Maturation Antigen (BCMA) are provided as well as methods of depleting BCMA-expressing cells in a patient in need thereof, comprising administering a therapeutically effective amount of the antibody species or an entity comprising a BCMA binding fragment thereof. Methods of treating B cell-related disorders associated with BCMA expression in a patient in need thereof are provided, comprising administering to the patient a therapeutically effective amount of the antibody species or an entity comprising a BCMA binding fragment thereof.本發明提供結合B細胞成熟抗原(BCMA)之抗體物質以及耗盡有需要之患者中之BCMA表現細胞的方法，該方法包含投與治療有效量之該等抗體物質或包含其BCMA結合片段之實體。提供治療有需要之患者的與BCMA表現相關之B細胞相關病症的方法，其包含向該患者投與治療有效量之該等抗體物質或包含其BCMA結合片段之實體。
