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DÉRIVÉS D'IMIDAZO-PYRAZINE UTILES EN TANT QU'ACTIVATEURS DE GUANYLATE CYCLASES SOLUBLES
专利权人:
Merck Sharp & Dohme Corp.
发明人:
申请号:
EP15802906.6
公开号:
EP3152214A4
申请日:
2015.05.29
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
A compound of Formula II or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate ("cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula II, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula II or a pharmaceutically acceptable salt thereof.
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