Dérivés de 4-amino-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one ou 4-amino-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one en tant qu'activateurs de la cyclase du guanylat soluble pour le traitement de maladies cardio-vasculaires

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

申请号：

EP09830834.9

公开号：

EP2373317B1

申请日:

2009.11.16

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Compounds of Formula I are capable of modulating the body's production of cyclic guanosine monophosphate (&ldquo；cGMP&rdquo；) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of the Formula I, to their use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of the Formula I.

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