The endoscope apparatus performs observation using reflected light of white light generated in response to irradiation of white light to an object and observation using fluorescence generated according to irradiation of excitation light to the fluorescent dye An objective optical system into which an insertion portion that can be inserted into a subject, reflected light of white light, fluorescence, and reflected light of excitation light are incident, and light that is emitted through the objective optical system An optical filter arranged on the optical path up to the light incident from the objective optical system to the spectroscope and blocking the reflected light of the excitation light while transmitting the reflected light and the fluorescence of the white light And a plurality of image pickup devices for respectively picking up images of light emitted through the filter and the spectroscope.内視鏡装置は、被写体に対する白色光の照射に応じて発生する白色光の反射光を用いた観察と、蛍光色素に対する励起光の照射に応じて発生する蛍光を用いた観察と、を行うことができ、被検体内に挿入可能な挿入部と、白色光の反射光と、蛍光と、励起光の反射光と、が入射される対物光学系と、対物光学系を経て出射される光を分光する分光器と、対物光学系から入射した光が分光器に至るまでの光路上に配置され、白色光の反射光及び蛍光を透過させつつ励起光の反射光を遮断する光学フィルタと、光学フィルタ及び分光器を経て出射される光をそれぞれ撮像するための複数の撮像素子と、を有する。