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AQUEOUS SUSPENSIONS OF RILUZOLE
专利权人:
ITALFARMACO SPA
发明人:
DANIELE BARBARESCHI,JAIME MOSCOSO,MARCO ADAMI,PAOLO MASCAGNI,ROBERTA ARTICO,TIZIANO OLDONI
申请号:
BRPI1006418
公开号:
BRPI1006418A2
申请日:
2010.03.02
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
Physically and chemically stable aqueous suspensions of riluzole are disclosed together with the manufacturing methods thereof. Such aqueous suspensions comprise riluzole in particle form and at least a wetting agent, preferably a surfactant. Riluzole is in amounts from about 0.1 % to about 20% w/v and has an average particle size lower than 200 µm; such suspensions are devoided of the known local (mouth) anaesthetic effects of riluzole.
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