Refers to a sustained Release Pharmaceutical composition comprising the compound 2 - feniltiazol: formula (i) where R1 is C1 - alkoxy Group 8, a morpholino metilpiperazin - 1, 4 - or - ilo piperidino R2 is Nitro or cyano X is alcoxicarbonilo C2 carboxyl or - 7 and is Hydrogen or alkyl C1 - 6. A Preferred Compound is acid 2 - (3 - cyano - 4 - isobutiloxifenil) - 4 - methyl - 5 - thiazole carboxylic acid.The pharmaceutical composition is useful for the Treatment or prevention of hypertension, High Blood Pressure normal and renal dysfunctionSE REFIERE A UNA COMPOSICION FARMACEUTICA DE LIBERACION SOSTENIDA QUE COMPRENDE EL COMPUESTO 2-FENILTIAZOL DE FORMULA (I) DONDE: R1 ES ALCOXI C1-8, UN GRUPO MORFOLINO, 4-METILPIPERAZIN-1-ILO O PIPERIDINO R2 ES NITRO O CIANO X ES CARBOXILO O ALCOXICARBONILO C2-7 Y ES HIDROGENO O ALQUILO C1-6. UN COMPUESTO PREFERIDO ES ACIDO 2-(3-CIANO-4-ISOBUTILOXIFENIL)-4-METIL-5-TIAZOL CARBOXILICO. DICHA COMPOSICION FARMACEUTICA ES UTIL PARA EL TRATAMIENTO O PREVENCION DE LA HIPERTENSION, PRESION SANGUINEA ALTA NORMAL Y DISFUNCION RENAL