The Regents of the University of Colorado, A Body Corporate; Inc.;Xalud Therapeutics;Xalud Therapeutics, Inc.
发明人:
CHAVEZ, Raymond, A.,WATKINS, Linda, R.,LANDRY, Robert,CHAVEZ RAYMOND A,WATKINS LINDA R,LANDRY ROBERT
申请号：
DK14826787
公开号：
DK3021873T3
申请日:
2014.07.17
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
This invention provides compositions and methods for preventing inflammatory diseases of the joints, including rheumatoid and osteoarthritis, tendonitis, bursitis, inflammation of the ligament, synovitis, gout and systemic lupus erythematosus, wherein the methods include injecting into the inflamed joint a therapeutic anti-inflammatory composition comprising a bacterial or vial IL-10 expression construct, wherein the IL-10 expression construct comprises a bacterial or viral backbone and a nucleic acid sequence encoding interleukin-10.
