The Regents of the University of Colorado, a Body Corporate;Xalud Therapeutics, Inc.
发明人:
Raymond A. Chavez,Linda R. Watkins,Robert Landry
申请号：
US14905915
公开号：
US10512672B2
申请日:
2014.07.17
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This invention provides compositions and methods for preventing inflammatory diseases of the joints, including rheumatoid and osteoarthritis, tendonitis, bursitis, inflammation of the ligament, synovitis, gout, and systemic lupus erythematosus, wherein the methods include injecting into the inflamed joint a therapeutic anti-inflammatory composition comprising a bacterial or viral IL-10 expression construct, wherein the IL-10 expression construct comprises a bacterial or viral backbone and a nucleic acid sequence encoding interleukin-10.
