The invention relates to a patch (1) for regenerating biological tissues in patients, and associated production method, comprising a collagen membrane (2) having cells of a regenerative nature, and at least one reinforcing element (3a, 3b) configured for increasing the rigidity of the membrane (2), preventing the deformation of the membrane (2) during handling, wherein the reinforcing element (3a, 3b) can be a peripheral frame (3a) and/or a cross-piece (3b) between the edges of the membrane (2), resulting in a patch (1) that can be applied to any kind of biological organ with the maximum guarantee of success, and a shorter application time.
