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MULTIPLEX ASSAY METHOD USING MAGNETIC LABELS AND DEVICE FOR THE IMPLEMENTATION THEREOF
专利权人:
NIKITIN, Petr Ivanovich
发明人:
NIKITIN, Petr Ivanovich
申请号:
WO2017RU00724
公开号:
WO2018063034(A1)
申请日:
2017.09.29
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
The invention relates to the field of biotechnology and medicine, and more particularly to the field of biochemical analysis, and makes it possible to determine the quantitative concentration of multiple analytes in a sample simultaneously. A method and device for the simultaneous multiplex determination of multiple analytes in a liquid sample are based on the use of modules in the form of immunochromatographic test strips and the use of magnetic particles as detectable labels. At least one reading zone is formed on each module (test strip), said reading zone being capable of interacting with an analyte in a sample and selectively (specifically) binding magnetic labels conjugated with recognition receptors. A multiplex device is formed from a set of modules with spaced apart reading zones, said modules being disposed in a cartridge made of a material that is permeable to an external magnetic field, which is provided with a region for allowing migration of the sample along all of the modular test strips. The n
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