The invention relates to a system and method for isolating particles from a biological fluid, including: obtaining a sample of biological fluid from a source (e.g. a patient) in which the sample contains particles of multiple sample particle types tagging particles in the sample with tagging agents, including mixing the sample with a solution of magnetic tagging agents that selectively bind to particles of at least one of the sample particle types, thereby forming a group of tagged particles in the sample passing the sample through a magnetic conduit having a magnetic field that interacts with at least some of the tagged particles sorting the particles of the sample into multiple groups based on the interaction between the tagged particles and the magnetic field and optionally returning selected portions of the processed fluid back to its source with or without the addition of appropriate therapeutic agents.