An inhaler (1) for delivering a powdered medicament (2) to a user from a container (4), comprising a flow channel (6), an opening means (8) and a housing (10). The flow channel comprises a conduit (16) extending from an inlet (18) to an outlet (20) and including a medicament introduction region (22). The housing includes a loading member (24) coupled thereto which includes a holder (26) for receiving and retaining the container. The loading member can be manually moved by a user between a loading position, in which a container can be manually loaded into the holder, and an inhalation position in which the medicament in the container can be introduced into the flow channel. The movement of the loading member from the loading position to the inhalation position causes the opening means to break a seal on the container, thereby exposing the medicament for introduction into the flow channel.
