An adjustable angle targeting device for an intramedullary nail includes a frame, a drill guide, and a holding member with both the drill guide and the holding member supported by the frame. The holding member includes a spherical upper surface, a lower surface, a first rotational alignment member for aligning the intramedullary nail with the holding member, and a bore extending through the holding member. The bore includes a circular lower portion opening to the lower surface and a slot shaped upper portion opening to the upper surface and having a length greater than the diameter of the circular lower portion. The targeting device further includes a holding bolt for insertion through the bore. The holding bolt includes a coupling portion for coupling with the intramedullary nail and axially aligning the intramedullary nail and a head with a bottom surface shaped complementary to the upper surface of the holding member.