A composition for restraining fat formation and promoting antioxidative activity includes an effective dose of Rhodiola extract, a glycerylphosphoryl choline and a pharmaceutically acceptable vehicle or salt thereof. Based on animal experiments, the combination of Rhodiola extract and glycerylphosphoryl choline not only effectively lowers body fat in animal bodies, but also provides high antioxidative activity.本發明提供一種具抑制脂肪形成及抗氧化活性之組合物,組合物包含有效劑量之一紅景天萃取物及一甘油磷酸膽鹼及其醫藥可接受載劑或醫藥可接受鹽。經動物實驗證實,透過紅景天萃取物與甘油磷酸膽鹼的混合,能有效降低動物體內的體脂肪,還可提高抗氧化的效果。