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Compositions and methods related to inhibitors of JAK kinase
专利权人:
发明人:
Federica Pericle,Jeremy A. Ross
申请号:
US14387890
公开号:
US09371265B2
申请日:
2013.03.26
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Embodiments are directed to JAK kinase inhibiting prodrug compounds of Formula Ib, containing a promoiety that results in alcohol derivative of the parent compound upon removal and methods of using an effective amount of said prodrug compounds in the treatment of a JAK-mediated disease or disorder in a subject. Preferred promoieties include phosphate, phosphonate, phosphate salt, sulfate, or sulfate salt.
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