SELS DE CITRATE D'UN INHIBITEUR DE KINASE DE JANUS (JAK)

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专利权人:

SANDOZ AG

发明人:

申请号：

EP16201249.6

公开号：

EP3327020A1

申请日:

2016.11.29

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to citrate salts of baricitinib, in particular to baricitinib mono- and dicitrate, as well as to crystalline and amorphous forms thereof, and to methods for their preparation. Furthermore, the invention relates to a pharmaceutical composition comprising an effective and/or predetermined amount of one or more citrate salts of baricitinib and to the use of said pharmaceutical composition as a medicament, in particular for the treatment of rheumatoid arthritis.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/